Adaptation of Influenza A/Mallard/Potsdam/178-4/83 H2N2 Virus in Japanese Quail Leads to Infection and Transmission in Chickens

Abstract excerpt

To assess the potential of quail as an intermediate host of avian influenza, we tested the influenza A/Mallard/ Potsdam/178-4/83 (H2N2) virus to determine whether through adaptation a mallard strain can replicate and transmit in quail, as well as other terrestrial birds. After five serial passages of lung homogenate a virus arose that replicated and transmitted directly to contact cage mates. To test whether...

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