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Investigation of Adenovirus Occurrence in Pediatric Tumor Entities

9 May 2007

Abstract excerpt

Adenoviruses (AdVs) contain genes coding for proteins with transforming potential, and certain AdV serotypes have been shown to induce tumors in rodents. However, data on the possible oncogenicity of AdVs in humans are scarce. We have therefore employed a real-time quantitative PCR (RQ-PCR) assay permitting highly sensitive detection of all 51 currently known human AdV serotypes to screen more than 500 tumor...

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PMID: 17494079
DOI: 10.1128/jvi.00355-07

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