Article
[Association analysis of gene polymorphism in alcohol metabolizing enzymes with risk for coronary atherosclerosis].
Genetika - 1 Mar 2007
Marusin A V, Stepanov V A, Spiridonova M G, Khar'kov V A, Pel's Ia R, Puzyrev V P
Abstract excerpt
The allele and genotype distribution of two alcohol dehydrogenase genes ADH1B (exon 3 polymorphism A/G (47His)), ADH7 (intron 5 polymorphism G/C) and cytochrome P450 2E1 gene (CYP2E1; 5'-flanking region G/C and intron 6 T/A polymorphisms) were examined in Russian (Tomsk, n = 125) healthy population and in coronary atherosclerosis patients (CA, n = 92). The genotype frequencies followed the Hardy-Weinberg...
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