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Article

Conservation of the pentanucleotide motif at the top of the yellow fever virus 17D 3' stem-loop structure is not required for replication.

The Journal of general virology - 1 Jun 2007

Silva Patrícia A G C, Molenkamp Richard, Dalebout Tim J, Charlier Nathalie, Neyts Johan H, Spaan Willy J M, Bredenbeek Peter J

Abstract excerpt

The pentanucleotide (PN) sequence 5'-CACAG-3' at the top of the 3' stem-loop structure of the flavivirus genome is well conserved in the arthropod-borne viruses but is more variable in flaviviruses with no known vector. In this study, the sequence requirements of the PN motif for yellow fever virus 17D (YFV) replication were determined. In general, individual mutations at either the second, third or fourth...

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Identifiers

PMID: 17485534
DOI: 10.1099/vir.0.82811-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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