Article
Aflatoxin production via cross-feeding of pathway intermediates during cofermentation of aflatoxin pathway-blocked Aspergillus parasiticus mutants.
Applied and environmental microbiology - 1 Oct 1991
Cleveland T E, Bhatnagar D, Brown R L
Abstract excerpt
Cofermentation of Aspergillus parasiticus strains (SRRC 163 and SRRC 2043) blocked at different steps in the aflatoxin B1 (AFB1) biosynthetic pathway in a synthetic liquid medium or on seeds (cottonseed, corn kernels, and peanuts) resulted in production of AFB1. Strain SRRC 2043 accumulated O-methylsterigmatocystin (OMST), a late precursor in AFB1 biosynthesis, whereas SRRC 163 accumulated averantin, an early...
Topics
- Aflatoxin B1
- Aspergillus
- Culture Media
- Fermentation
- Genetic Complementation Test
- Mutation
