Article
Bypassing genomic imprinting allows seed development.
Nature - 17 May 2007
Nowack Moritz K, Shirzadi Reza, Dissmeyer Nico, Dolf Andreas, Endl Elmar, Grini Paul E, Schnittger Arp
Abstract excerpt
In developing progeny of mammals the two parental genomes are differentially expressed according to imprinting marks, and embryos with only a uniparental genetic contribution die. Gene expression that is dependent on the parent of origin has also been observed in the offspring of flowering plants, and mutations in the imprinting machinery lead to embryonic lethality, primarily affecting the development of the...
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