Article
Predictive factors for long-term effects of imatinib therapy in patients with inoperable/metastatic CD117(+) gastrointestinal stromal tumors (GISTs).
Journal of cancer research and clinical oncology - 1 Sept 2007
Rutkowski Piotr, Nowecki Zbigniew I, Debiec-Rychter Maria, Grzesiakowska Urszula, Michej Wanda, Woźniak Agnieszka, Siedlecki Janusz A, Limon Janusz, vel Dobosz Anna Jerzak, Kakol Michał, Osuch Czesław, Ruka Włodzimierz
Abstract excerpt
THE PURPOSE: To analyze the outcomes of treatment and factors predicting effects of imatinib (IM) therapy in inoperable/metastatic gastrointestinal stromal tumors (GIST) CD117(+) patients. MATERIALS AND METHODS: We identified 232 patients in a prospectively collected Clinical GIST Registry with advanced inoperable/metastatic GIST treated with IM 400-800 mg daily (129 males and 103 females and median age 56...
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