Expression and purification of an active cysteine protease of Haemonchus contortus using Caenorhabditis elegans.

Abstract excerpt

Many proteolytic enzymes of parasitic nematodes have been identified as possible targets of control. Testing these as vaccine or drug targets is often difficult due to the problems of expressing proteases in a correctly folded, active form in standard expression systems. In an effort to overcome these difficulties we have tested Caenorhabditis elegans as an expression system for a Haemonchus contortus cathepsin L...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cysteine Endopeptidases
• Share to Enhancer Elements, Genetic