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Article

Stress molecules in sepsis and systemic inflammatory response syndrome

4 Apr 2007

Abstract excerpt

During sepsis, microbial derived products ("pathogen-associated molecular patterns", PAMPs) are recognized as exogenous danger signals by specific sensors of the host ("pattern recognitions receptors", PRRs). This interaction leads to the release of numerous stress proteins that are a prerequisite to fight infection, though their overzealous production can contribute to tissue damage, organ dysfunction and...

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PMID: 17428476
DOI: 10.1016/j.febslet.2007.03.074

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