Article
Single-nucleotide polymorphisms and lung disease: clinical implications.
Chest - 1 Apr 2007
Tebbutt Scott J, James Alan, Paré Peter D
Abstract excerpt
Human genetic variation has enormous implications for individual susceptibility to lung disease, as well as for differences in prognosis and response to therapeutic interventions. Single-nucleotide polymorphisms (SNPs) are the most common type of DNA sequence variation. An SNP is the substitution of a single base in the sequence for one that is different from that present in the majority of the population. In...
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