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Article

Preimplantation genetic diagnosis for fragile X syndrome using multiplex nested PCR.

Reproductive biomedicine online - 1 Apr 2007

Malcov Mira, Naiman Tova, Yosef Dalit Ben, Carmon Ariella, Mey-Raz Nava, Amit Ami, Vagman Israel, Yaron Yuval

Abstract excerpt

Fragile X syndrome is caused by a dynamic mutation in the FMR1 gene. Normal individuals have <55 CGG repeats in the 5 untranslated region, premutation carriers have 55-200 repeats and a full mutation has >200 repeats. Female carriers are at risk of having affected offspring. A multiplex nested po...

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Source

Identifiers

PMID: 17425837
DOI: 10.1016/s1472-6483(10)60901-7

Genes

FMR1
PGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17425837-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Preimplantation genetic diagnosis for fragile X syndrome using multiplex nested PCR.PMID 17425837Read ↗

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