Triosephosphate isomerase deficiency: facts and doubts.

doi:10.1080/15216540601115960

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Article

Triosephosphate isomerase deficiency: facts and doubts.

IUBMB life - 1 Dec 2006

Orosz Ferene, Oláh Judit, Ovádi Judit

Abstract excerpt

Many glycolytic enzymopathies have been described that manifest clinically as chronic hemolytic anemia. One of these, triosephosphate isomerase (TPI) deficiency, is unique among the glycolytic enzyme defects since it is associated with progressive neurological dysfunction and frequently with childhood death. The physiological function of TPI is to adjust the rapid equilibrium between dihydroxyacetone phosphate...

Topics

Anemia, Hemolytic, Congenital Nonspherocytic
Brain
Energy Metabolism
Erythrocytes
Glycolysis
Humans
Male
Models, Molecular
Mutation
Triose-Phosphate Isomerase

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Open in PubMed

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PMID: 17424909
DOI: 10.1080/15216540601115960

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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