World Health Organization classification in combination with cytogenetic markers improves the prognostic stratification of patients with <i>de novo</i> primary myelodysplastic syndromes

Abstract excerpt

This study correlated chromosomal defects with French-American-British (FAB)/World Health Organization (WHO) classification subtypes, proposed a revised International Prognostic Scoring System (IPSS) cytogenetic grouping; and established which classification, when used with the IPSS cytogenetic categories, best predicted clinical outcome in the myelodysplastic syndromes (MDS). A higher prevalence of chromosomal...

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