Article
Nutri-epigenomics: lifelong remodelling of our epigenomes by nutritional and metabolic factors and beyond.
Clinical chemistry and laboratory medicine - 1 Jan 2007
Gallou-Kabani Catherine, Vigé Alexandre, Gross Marie-Sylvie, Junien Claudine
Abstract excerpt
The phenotype of an individual is the result of complex interactions between genotype, epigenome and current, past and ancestral environment, leading to lifelong remodelling of our epigenomes. Various replication-dependent and -independent epigenetic mechanisms are involved in developmental programming, lifelong stochastic and environmental deteriorations, circadian deteriorations, and transgenerational effects....
Topics
- Circadian Rhythm
- Diet
- Environment
- Epigenesis, Genetic
- Gene Expression Regulation
- Humans
- Nutritional Status
- Phenotype