Article
[Nutritionnal epigenomics: consequences of unbalanced diets on epigenetics processes of programming during lifespan and between generations].
Annales d'endocrinologie - 1 Apr 2005
Junien C, Gallou-Kabani C, Vigé A, Gross M-S
Abstract excerpt
Epigenetic changes associated with DNA methylation and histone modifications leading to chromatin remodeling and regulation of gene expression underlie the developmental programming of obesity, type 2 diabetes, cardiovascular diseases and metabolic syndrome. This review focuses on converging data supporting the hypothesis that, in addition to "thrifty genotype" inheritance, individuals with obesity, type 2...
Topics
- Adult
- Child
- Child, Preschool
- Diabetes Mellitus, Type 2
- Diet
- Female
- Fetal Development
- Genomics
- Genotype
- Humans
- Infant
- Infant, Newborn
