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Article

Noncell-autonomous photoreceptor degeneration in a zebrafish model of choroideremia.

Proceedings of the National Academy of Sciences of the United States of America - 13 Mar 2007

Krock Bryan L, Bilotta Joseph, Perkins Brian D

Abstract excerpt

Choroideremia is an X-linked hereditary retinal degeneration resulting from mutations in the Rab escort protein-1 (REP1). The Rep1 protein facilitates posttranslational modification of Rab proteins, which regulate intracellular trafficking in the retinal pigment epithelium (RPE) and photoreceptors and are likely involved in the removal of outer segment disk membranes by the RPE. A critical question for potential...

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Share to Choroideremia
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microscopy, Electron, Transmission

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Share to Photoreceptor Cells, Vertebrate

Share to Pigment Epithelium of Eye

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Source

Open in PubMed Open full text

Identifiers

PMID: 17360570
DOI: 10.1073/pnas.0605818104
PMCID: PMC1810335

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Noncell-autonomous photoreceptor degeneration in a zebrafish model of choroideremia.PMID 17360570Read ↗

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