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Vascular and Cellular Stress in Inflammatory Bowel Disease: Revisiting the Role of Homocysteine

13 Mar 2007

Abstract excerpt

Moderate hyperhomocysteinemia is a complex trait commonly associated with inflammatory bowel disease (IBD). Nutritional deficiencies and genetic determinants have been identified as risk factors for moderate hyperhomocysteinemia, such as folate and vitamin B(12) deprivation and polymorphisms in the 5,10 methylenetetrahydrofolate reductase (MTHFR) encoding gene, respectively. Homocysteine has a crucial role in...

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PMID: 17355415
DOI: 10.1111/j.1572-0241.2007.01170.x

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