Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular mechanisms of resistance to antiviral therapy in patients with chronic hepatitis B.

Current molecular medicine - 1 Mar 2007

Yuan He-Jun, Lee William M

Abstract excerpt

Similar to the human immunodeficiency virus (HIV), the hepatitis B virus (HBV) replicates via reverse transcription, in this case, within infected hepatocytes. Substantial advances have been achieved in the past ten years in developing and utilizing nucleoside/nucleotide analog drugs to inhibit HBV replication. Most are chain terminators that interfere with one or more steps in the replication cycle. Four of them...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to Clinical Trials as Topic
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Therapy, Combination

Share to Hepatitis B, Chronic

Share to Hepatitis B virus

Share to Interferons

Share to Virus Replication

Source

Identifiers

PMID: 17346170
DOI: 10.2174/156652407780059159

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular mechanisms of resistance to antiviral therapy in patients with chronic hepatitis B.PMID 17346170Read ↗

Chronic hepatitis B therapy: available drugs and treatment guidelines.Semantic proximity Read ↗

Update on hepatitis B virus infection.Semantic proximity Read ↗

Hepatitis B virus drug resistance to current nucleos(t)ide analogs: Mechanisms and mutation sitesSemantic proximity Read ↗

Influence of mutations in the hepatitis B virus genome on virus replication and drug resistance--implications for novel antiviral strategies.Semantic proximity Read ↗

Treatment of chronic hepatitis B: current challenges and future directions.Semantic proximity Read ↗

Chronic hepatitis B: preventing, detecting, and managing viral resistance.Semantic proximity Read ↗

Treatment modalities for hepatitis B viral infection and resistance to antiviral therapy.Semantic proximity Read ↗

Comparison of the Mechanisms of Drug Resistance among HIV, Hepatitis B, and Hepatitis CSemantic proximity Read ↗

Viral resistance in hepatitis B: prevalence and management.Semantic proximity Read ↗

Mechanism of viral persistence and resistance to nucleoside and nucleotide analogs in chronic Hepatitis B virus infectionSemantic proximity Read ↗

Mechanism of viral persistence and resistance to nucleoside and nucleotide analogs in chronic hepatitis B virus infection.Semantic proximity Read ↗

Treatment for hepatitis B in patients with drug resistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.