Article
Altered proteome in Burkholderia pseudomallei rpoE operon knockout mutant: insights into mechanisms of rpoE operon in stress tolerance, survival, and virulence.
Journal of proteome research - 1 Apr 2007
Thongboonkerd Visith, Vanaporn Muthita, Songtawee Napat, Kanlaya Rattiyaporn, Sinchaikul Supachok, Chen Shui-Tein, Easton Anna, Chu Karen, Bancroft Gregory J, Korbsrisate Sunee
Abstract excerpt
We have previously shown that the alternative sigma factor sigmaE (RpoE), encoded by rpoE, is involved in stress tolerance and survival of Burkholderia pseudomallei. However, its molecular and pathogenic mechanisms remain unclear. In the present study, we applied gel-based, differential proteomics to compare the cellular proteome of an rpoE operon knockout mutant (RpoE Mut) to that of wild-type (K96243 WT) B....
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