Article
Prenatal diagnosis in monozygotic twins with Down syndrome who had different phenotypes.
Prenatal diagnosis - 1 Jun 2007
Grynberg M, Graesslin O, Teyssedre J, Quereux C, Gaillard D, Carré-Pigeon F
Abstract excerpt
We report the case of monozygotic (MZ) male twin fetuses with different Down syndrome (DS) phenotypes. Prenatal fetal sonography showed a bichorial biamniotic pregnancy with increased nuchal translucency in twin A and a cervical cystic hygroma and heart defect in twin B. Cytogenetic analysis performed after double amniocentesis showed free and homogeneous trisomy 21 in both twins. Monozygosity was confirmed by...
Topics
- Abortion, Induced
- Diseases in Twins
- Down Syndrome
- Female
- Humans
- Male
- Phenotype
- Pregnancy
- Twins, Monozygotic
- Ultrasonography, Prenatal