Article
Are beta-lactam breakpoints adequate to define non-susceptibility for all Haemophilus influenzae resistance phenotypes from a pharmacodynamic point of view?
The Journal of antimicrobial chemotherapy - 1 Apr 2007
Alou L, Giménez M J, Sevillano D, Aguilar L, González N, Echeverría O, Torrico M, Coronel P, Prieto J
Abstract excerpt
OBJECTIVES: To investigate the bactericidal activity, against Haemophilus influenzae strains exhibiting different resistance phenotypes, of simulated serum concentrations obtained in humans after administration of 400 mg of cefditoren twice daily, 500 mg of cefuroxime twice daily, 875/125 mg of co-amoxiclav twice daily or 875/125 mg of co-amoxiclav three times daily. METHODS: An in vitro computerized...
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