Article
High-resolution genotyping of Chlamydia trachomatis strains by multilocus sequence analysis.
Journal of clinical microbiology - 1 May 2007
Klint Markus, Fuxelius Hans-Henrik, Goldkuhl Renée Röstlinger, Skarin Hanna, Rutemark Christian, Andersson Siv G E, Persson Kenneth, Herrmann Björn
Abstract excerpt
Genotyping of Chlamydia trachomatis is limited by the low sequence variation in the genome, and no adequate method is available for analysis of the spread of chlamydial infections in the community. We have developed a multilocus sequence typing (MLST) system based on five target regions and compared it with analysis of ompA, the single gene most extensively used for genotyping. Sequence determination of 16...
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