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Article

Muscleblind isoforms are functionally distinct and regulate alpha-actinin splicing.

Differentiation; research in biological diversity - 1 Jun 2007

Vicente Marta, Monferrer Lidón, Poulos Michael G, Houseley Jonathan, Monckton Darren G, O'dell Kevin M C, Swanson Maurice S, Artero Rubén D

Abstract excerpt

Drosophila Muscleblind (Mbl) proteins control terminal muscle and neural differentiation, but their molecular function has not been experimentally addressed. Such an analysis is relevant as the human Muscleblind-like homologs (MBNL1-3) are implicated in the pathogenesis of the inherited muscular developmental and degenerative disease myotonic dystrophy. The Drosophila muscleblind gene expresses four protein...

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Identifiers

PMID: 17309604
DOI: 10.1111/j.1432-0436.2006.00156.x

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MBNL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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An Overview of Alternative Splicing Defects Implicated in Myotonic Dystrophy Type ISemantic proximity Read ↗

Expanded CUG Repeats Dysregulate RNA Splicing by Altering the Stoichiometry of the Muscleblind 1 ComplexSemantic proximity Read ↗

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