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Article

A phase II trial of carboplatin for intraocular retinoblastoma

14 Feb 2007

Abstract excerpt

BACKGROUND: Retinoblastoma patients with RB1 germline mutations are at risk of developing second malignancies and external beam radiation therapy increases the risk. Carboplatin-containing chemotherapy regimens in conjunction with local therapies have been investigated for intraocular retinoblastoma, but the lack of data regarding the efficacy of single agent intravenous carboplatin prompted this phase II study....

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Identifiers

PMID: 17301956
DOI: 10.1002/pbc.21163

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