Article
Effect of the different phosphorylated Smad2 protein localizations on the invasive breast carcinoma phenotype.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Feb 2007
Liapis George, Mylona Eleni, Alexandrou Paraskevi, Giannopoulou Ioanna, Nikolaou Irini, Markaki Sofia, Keramopoulos Antonios, Nakopoulou Lydia
Abstract excerpt
Smad2 participates in the TGF-beta signaling pathway, where it cooperates with transcription factors to regulate expression of defined genes. The purpose of this study was to investigate the expression pattern of phosphorylated Smad2 (pSmad2) in association with clinicopathological parameters and biological markers of proliferation and invasion. Immunohistochemistry was applied on paraffin-embedded sections from...
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