Article
[An association study between GRIN1, BDNF genes and bipolar disorder].
Yi chuan = Hereditas - 1 Jan 2007
Liu Min, Ling Si-Hai, Li Wen-Biao, Wang Chuan-Yue, Chen Da-Fang, Wang Gang
Abstract excerpt
To evaluate the role of inherited gene variations in GRIN1 (glutamate receptor, ionotropic NMDA1), BDNF (brain derived neurotrophic factor) genes in human bipolar disorder, we selected 4 single nucleotide polymorphisms in GRIN1, BDNF (2 SNPs in each gene) and made SNPs analysis in 100 unrelated cases and 100 controls by TaqMan. Then we compared genotypes differences between cases and controls. The software SHEsis...
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