Article
The molecular biology of addictive drugs.
Molecular neurobiology - 1 Jan 1991
Mackler S A, Eberwine J H
Abstract excerpt
The additive drugs alcohol, morphine, cocaine, and amphetamine are each associated with the development of tolerance and physical dependence. Changes in gene expression occur in cell culture and in vivo with the administration of these centrally-acting drugs. This article reviews those experiments that have studied drug-induced alterations in gene transcription. Ethanol has diverse effects on the amounts of...
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