Article
Role of alterations in the apoptotic machinery in sensitivity of cancer cells to treatment.
Current pharmaceutical design - 1 Jan 2006
Rodriguez-Nieto Salvador, Zhivotovsky Boris
Abstract excerpt
Apoptosis is a genetically controlled and evolutionarily conserved form of cell death of critical importance for normal embryonic development and for the maintenance of tissue homeostasis in the adult organism. The malfunction of the death machinery may play a primary or secondary role in various...
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