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Article

Expression of TGF-beta signaling proteins in normal placenta and gestational trophoblastic disease.

1 Mar 2007

Abstract excerpt

The transforming growth factor beta (TGF-beta) is a vital regulator of placental development and functions. TGF-beta exerts several modulatory effects on trophoblast cells, such as inhibition of proliferation and invasiveness, and stimulation of differentiation by inducing multinucleated cell formation. In this study, we determine the expression patterns of TGF-beta signaling molecules in normal trophoblast,...

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PMID: 17163397
DOI: 10.14670/hh-22.227

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