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Article

Protein homology network families reveal step-wise diversification of Type III and Type IV secretion systems.

PLoS computational biology - 1 Dec 2006

Medini Duccio, Covacci Antonello, Donati Claudio

Abstract excerpt

From the analysis of 251 prokaryotic genomes stored in public databases, the 761,260 deduced proteins were used to reconstruct a complete set of bacterial proteic families. Using the new Overlap algorithm, we have partitioned the Protein Homology Network (PHN), where the proteins are the nodes and the links represent homology relationships. The algorithm identifies the densely connected regions of the PHN that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17140285
DOI: 10.1371/journal.pcbi.0020173
PMCID: PMC1676029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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