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Staphylococcus aureus Subvert Autophagy for Induction of Caspase-independent Host Cell Death

30 Nov 2006

Abstract excerpt

Staphylococcus aureus is a common bacterial etiology of serious infectious diseases. S. aureus can invade various types of non-professional phagocytes to produce host cell death. We show here that shortly after invasion of HeLa cells S. aureus transit to autophagosomes was characterized by double membranes and co-localization with LC3. S. aureus were not able to replicate and produce cell death in...

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PMID: 17135247
DOI: 10.1074/jbc.m609784200

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