Article
The phenotypically variable surface protein of Trichomonas vaginalis has a single, tandemly repeated immunodominant epitope.
Infection and immunity - 1 Jun 1991
Dailey D C, Alderete J F
Abstract excerpt
Trichomonas vaginalis is a sexually transmitted protozoan parasite that undergoes phenotypic variation for numerous surface proteins. A monoclonal antibody (MAb) was used to isolate an approximately 400-bp cDNA encoding a fragment of an important phenotypically varying immunogen of T. vaginalis (Mr = 270 kDa; P270). The MAb completely inhibited the binding of P270 by antibody in sera of patients and by antibody...
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