Article
Structure and function of C1-inhibitor.
Immunology and allergy clinics of North America - 1 Nov 2006
Wagenaar-Bos Ineke G A, Hack C Erik
Abstract excerpt
C1-INH belongs to the family of serpins. Structural studies have yielded a clear understanding of the biochemical principle underlying the functional activities of these proteins. Although the crystal structure of C1-INH has yet to be revealed, homology modeling has provided a three-dimensional model of the serpin part of C1-INH. This model has helped us understand the biochemical consequences of mutations of the...
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