Article
Matching of the minor histocompatibility antigen HLA-A1/H-Y may improve prognosis in corneal transplantation.
Transplantation - 27 Oct 2006
Böhringer Daniel, Spierings Eric, Enczmann Jürgen, Böhringer Stefan, Sundmacher Rainer, Goulmy Els, Reinhard Thomas
Abstract excerpt
BACKGROUND: Minor histocompatibility (H) antigens are peptides of allelic intracellular proteins that play an important role in human leukocyte antigen (HLA) matched transplantations. In an animal model of keratoplasty, minor H antigens have even been reported to exceed the immunogenicity of major H antigens (MHC). This investigation is to assess any benefit of matching the broadly expressed gender (H-Y) and HA-3...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
