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Derivation of Clinically Compliant MSCs from CD105+, CD24− Differentiated Human ESCs

19 Oct 2006

Abstract excerpt

Adult tissue-derived mesenchymal stem cells (MSCs) have demonstrated therapeutic efficacy in treating diseases or repairing damaged tissues through mechanisms thought to be mediated by either cell replacement or secretion of paracrine factors. Characterized, self-renewing human ESCs could potentially be an invariable source of consistently uniform MSCs for therapeutic applications. Here we describe a clinically...

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PMID: 17053208
DOI: 10.1634/stemcells.2006-0420

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