Article
Recombination in feline lentiviral genomes during experimental cross-species infection.
Virology - 1 Mar 2007
Poss Mary, Idoine Adam, Ross Howard A, Terwee Julie A, VandeWoude Sue, Rodrigo Allen
Abstract excerpt
Domestic cats develop an asymptomatic, productive infection with a feline immunodeficiency virus (PLV) derived from a naturally infected cougar (P. concolor). We previously demonstrated that there are extensive G to A substitutions, characteristic of host cytidine deaminase editing, and positive selection on reverse transcriptase in the PLV genome during this cross-species infection. In this study, we evaluated...
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