Article
Safety, efficacy and pharmacokinetics of peginterferon alpha2a (40 kd) in children with chronic hepatitis C.
Journal of pediatric gastroenterology and nutrition - 1 Oct 2006
Schwarz Kathleen B, Mohan Parvathi, Narkewicz Michael R, Molleston Jean Pappas, Nash S Russell, Hu Sylvia, Wang Ka, Gries Jean Michel
Abstract excerpt
Chronic hepatitis C virus (HCV) infection in children is a problem affecting thousands of children worldwide. Although standard interferon (INF) has better efficacy in pediatric patients than in adults, results in children with genotype 1 are poor; response rates to combination treatment with standard INF and ribavirin are better but the treatment requires thrice-weekly injections. The improved antiviral efficacy...
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