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Article

Characterisation and confirmation of rare beta-thalassaemia mutations in the Malay, Chinese and Indian ethnic groups in Malaysia.

Pathology - 1 Oct 2006

Tan Jin Ai Mary Anne, Chin Pui See, Wong Yean Ching, Tan Kim Lian, Chan Lee Lee, George Elizabeth

Abstract excerpt

AIMS: In Malaysia, about 4.5% of the Malay and Chinese populations are heterozygous carriers of beta-thalassaemia. The initial identification of rare beta-globin gene mutations by genomic sequencing will allow the development of simpler and cost-effective PCR-based techniques to complement the existing amplification refractory mutation system (ARMS) and gap-PCR used for the identification of beta-thalassaemia...

Read the complete abstract on PubMed

Topics

Asian People
China
DNA Mutational Analysis
Genotype
Heterozygote
Humans
India

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Malaysia

Mutation

Polymerase Chain Reaction

beta-Thalassemia

Source

Identifiers

PMID: 17008283
DOI: 10.1080/00313020600922538

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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