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Prolactin in man: a tale of two promoters

22 Sept 2006

Abstract excerpt

The pituitary hormone prolactin (PRL) is best known for its role in the regulation of lactation. Recent evidence furthermore indicates PRL is required for normal reproduction in rodents. Here, we report on the insertion of two transposon-like DNA sequences in the human prolactin gene, which together function as an alternative promoter directing extrapituitary PRL expression. Indeed, the transposable elements...

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PMID: 16998840
DOI: 10.1002/bies.20468

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