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Article

A novel amyloidogenic transthyretin variant, Gly53Ala, associated with intermittent headaches and ataxia.

Journal of neurology, neurosurgery, and psychiatry - 1 Feb 2007

Douglass C, Suvarna K, Reilly M M, Hawkins P N, Hadjivassiliou M

Abstract excerpt

We report a novel transthyretin variant, Gly53Ala, in a 44-year-old British woman who presented with severe episodic headaches, often with focal neurological deficit, before developing progressive ataxia, depression, dementia and eventually peripheral neuropathy. Transthyretin amyloidosis was con...

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Identifiers

PMID: 16971399
DOI: 10.1136/jnnp.2006.093500
PMCID: PMC2077663

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16971399-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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