In situ hybridization: application to the study of gene expression during experimental hepatocarcinogenesis and human hepatocellular carcinoma.

doi:10.1159/000217652

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Article

In situ hybridization: application to the study of gene expression during experimental hepatocarcinogenesis and human hepatocellular carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 1990

Bernuau D, Feldmann G

Abstract excerpt

The possibility of detecting specific mRNA directly within tumor cells offered by the in situ hybridization (ISH) technique has provided a new dimension to the study of experimental and human hepatocarcinogenesis. The combination of ISH and immunocytochemical techniques on the same or adjacent ti...

Topics

Albumins
Animals
Carcinogens
Cell Differentiation
Cell Transformation, Neoplastic
DNA Replication
DNA, Viral
Gene Expression Regulation, Neoplastic
Hepatitis B virus
Humans
Liver Neoplasms, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nucleic Acid Hybridization

Phenotype

RNA, Messenger

RNA, Neoplasm

Rats

Virus Replication

alpha-Fetoproteins

Source

Open in PubMed

Identifiers

PMID: 1695388
DOI: 10.1159/000217652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1695388-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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