Article
Structural and functional comparison of the genes for human platelet factor 4 and PF4alt.
Blood - 15 Jul 1990
Eisman R, Surrey S, Ramachandran B, Schwartz E, Poncz M
Abstract excerpt
Platelet factor 4 (PF4) is a 70 amino acid heparin-binding protein released from the alpha-granules of activated platelets. Its exact biologic function is not known, although PF4 is a member of a multigene family involved in chemotaxis, coagulation, inflammation, and cell growth. We previously cl...
Topics
- Base Sequence
- Blood Platelets
- Cloning, Molecular
- DNA
- DNA Restriction Enzymes
- Humans
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Oligonucleotide Probes
- Platelet Factor 4
- Protein Sorting Signals
- Proteoglycans
- RNA
- Sequence Homology, Nucleic Acid