Article
Structural and functional comparison of the genes for human platelet factor 4 and PF4alt.
Blood - 15 Jul 1990
Eisman R, Surrey S, Ramachandran B, Schwartz E, Poncz M
Abstract excerpt
Platelet factor 4 (PF4) is a 70 amino acid heparin-binding protein released from the alpha-granules of activated platelets. Its exact biologic function is not known, although PF4 is a member of a multigene family involved in chemotaxis, coagulation, inflammation, and cell growth. We previously cloned the cDNA for human PF4 from a human erythroleukemic (HEL) cell expression library. We now report the isolation and...
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