Article
Diverse basal and stress-related phenotypes of Sprague Dawley rats from three vendors.
Physiology & behavior - 30 Nov 2006
Pecoraro Norman, Ginsberg Abigail B, Warne James P, Gomez Francisca, la Fleur Susanne E, Dallman Mary F
Abstract excerpt
Based on observed phenotypic differences in growth and ACTH responses to stress in Sprague Dawley rats obtained from different vendors, we ran head-to-head comparisons on rats obtained from three different vendors, Harlan, Charles River, and Simonsen, with respect to baseline phenotypic differences and a metabolic feedback hypothesis of hypothalamo-pituitary-adrenal (HPA) regulation. Charles River and Harlan rats...
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