Article
Occurrence of thrombotic events in acute promyelocytic leukemia correlates with consistent immunophenotypic and molecular features.
Leukemia - 1 Jan 2007
Breccia M, Avvisati G, Latagliata R, Carmosino I, Guarini A, De Propris M S, Gentilini F, Petti M C, Cimino G, Mandelli F, Lo-Coco F
Abstract excerpt
Although the occurrence of thrombosis in acute promyelocytic leukemia (APL) has been reported during retinoic acid treatment, no studies carried out in large clinical cohorts have specifically addressed this issue. We analyzed 124 APL patients treated with the all-trans retinoic acid and idarubicin protocol and compared clinico-biologic characteristics of 11 patients who developed thrombosis with those of 113...
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