Article
Presence of FLT3 mutations does not impair stem cell mobilization and feasibility of autologous peripheral blood stem cell transplantation in acute myeloid leukemia.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Sept 2006
Ferrara Felicetto, Palmieri Salvatore, Pollio Filiberto, Lo Pardo Catia, Graziano Daniela, Celentano Maria, D'Amico Maria Rosaria, Vicari Laura, Izzo Barbara, Pane Fabrizio
Abstract excerpt
Fetal liver tyrosine kinase 3 (FLT3) mutations represent a powerful prognostic indicator in acute myeloid leukemia (AML). Further, interaction between FLT3 and its ligand plays a role in normal hematopoiesis. Accordingly, FLT3 mutations may affect mobilization of peripheral blood stem cells (PBSC...
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