Article
Genes that can be mutated to unmask hidden antigenic determinants in the cuticle of the nematode Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America - 1 Apr 1990
Politz S M, Philipp M, Estevez M, O'Brien P J, Chin K J
Abstract excerpt
Rabbit antisera directed against a mixture of proteins solubilized from the wild-type adult Caenorhabditis elegans cuticle were used to isolate mutants, induced by ethyl methanesulfonate treatment, that exhibit alterations in surface antigenicity by immunofluorescence. Genetic mapping and complem...
Topics
- Animals
- Antigens, Helminth
- Antigens, Surface
- Caenorhabditis
- Epitopes
- Fluorescent Antibody Technique
- Genes
- Genetic Complementation Test
- Genotype
- Mutation
- Recombination, Genetic