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Article

Genes that can be mutated to unmask hidden antigenic determinants in the cuticle of the nematode Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 1 Apr 1990

Politz S M, Philipp M, Estevez M, O'Brien P J, Chin K J

Abstract excerpt

Rabbit antisera directed against a mixture of proteins solubilized from the wild-type adult Caenorhabditis elegans cuticle were used to isolate mutants, induced by ethyl methanesulfonate treatment, that exhibit alterations in surface antigenicity by immunofluorescence. Genetic mapping and complementation data for four such mutations define two genes, srf-2(I) and srf-3(IV). The mutant phenotypes observed by...

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Identifiers

PMID: 1691498
DOI: 10.1073/pnas.87.8.2901
PMCID: PMC53801

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Source receipt: pubmed, retrieved 7 Sept 2026.

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