Article
IrvA-dependent and IrvA-independent pathways for mutacin gene regulation in Streptococcus mutans.
FEMS microbiology letters - 1 Aug 2006
Tsang Phoebe, Merritt Justin, Shi Wenyuan, Qi Fengxia
Abstract excerpt
Streptococcus mutans is a primary pathogen associated with dental caries. Its bacteriocin (mutacin) production ability is thought to play an important role in maintaining competitiveness in the multispecies oral biofilm. Previous studies have demonstrated that the production of the lantibiotic, mutacin I, is responsive to multiple input signals and that a putative inducible repressor, irvA, seems to be involved...
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