Article
In situ characterization of cellular infiltrates in lupus vulgaris indicates lesional T-cell activation.
Archives of dermatology - 1 Mar 1990
Ramesh V, Samuel B, Misra R S, Nath I
Abstract excerpt
Skin biopsy specimens from nine patients with lupus vulgaris were examined in situ by means of monoclonal antibodies directed against phenotypes of lymphocyte subsets, Langerhans cells, HLA-DR antigens, and interleukin 2 receptor. The epidermis showed prominent changes, including intense expression of HLA-DR on keratinocytes, increase in epidermal cell layers, moderate to high Langerhans cell hyperplasia, and...
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