In situ characterization of cellular infiltrates in lupus vulgaris indicates lesional T-cell activation.

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Article

In situ characterization of cellular infiltrates in lupus vulgaris indicates lesional T-cell activation.

Archives of dermatology - 1 Mar 1990

Ramesh V, Samuel B, Misra R S, Nath I

Abstract excerpt

Skin biopsy specimens from nine patients with lupus vulgaris were examined in situ by means of monoclonal antibodies directed against phenotypes of lymphocyte subsets, Langerhans cells, HLA-DR antigens, and interleukin 2 receptor. The epidermis showed prominent changes, including intense expression of HLA-DR on keratinocytes, increase in epidermal cell layers, moderate to high Langerhans cell hyperplasia, and...

Topics

Adult
Antibodies, Monoclonal
Child
Epidermis
Epitopes
Female
HLA-DR Antigens
Humans
Immunoenzyme Techniques
Infant
Keratinocytes
Langerhans Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lupus Vulgaris

Lymphocyte Activation

Male

Middle Aged

Phenotype

Receptors, Interleukin-2

Source

Open in PubMed

Identifiers

PMID: 1689989

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1689989-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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