Article
The short vitamin D receptor is associated with increased risk for generalized aggressive periodontitis.
Journal of clinical periodontology - 1 Aug 2006
Park Kyung Sook, Nam Jung Hyun, Choi Jeomil
Abstract excerpt
BACKGROUND: Generalized aggressive periodontitis (GAP) exhibits severe inflammation and alveolar bone loss. Vitamin D receptor (VDR) regulates both bone metabolism and inflammation-related genes, and its polymorphisms and haplotypes may affect the functional activity of the VDR protein in GAP. OBJECTIVE: We analysed the genetic effect of VDR start codon, intron, and exon polymorphisms, and their haplotypes on the...
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