Article
Sperm protein "DE" mediates gamete fusion through an evolutionarily conserved site of the CRISP family.
Developmental biology - 1 Sept 2006
Ellerman Diego A, Cohen Débora J, Da Ros Vanina G, Morgenfeld Mauro M, Busso Dolores, Cuasnicú Patricia S
Abstract excerpt
The first member of the cysteine-rich secretory protein (CRISP) family was described by our laboratory in the rat epididymis, and it is known as DE or CRISP-1. Since then, numerous CRISPs exhibiting a high amino acid sequence similarity have been identified in animals, plants and fungi, although their functions remain largely unknown. CRISP-1 proteins are candidates to mediate gamete fusion in the rat, mouse and...
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